The included studies were initiated between 20, with the majority (63%) beginning in 2015 or later. Of the studies identified, those that had suspended, terminated, or otherwise unknown statuses were excluded. The database was queried using the term “minimally conscious state” in the “condition or disease” search parameter. In this report, we analyzed the database to systematically assess all clinical trials regarding MCS. This distinction is valuable in clinical practice, as minimally conscious patients may require different treatments and may have different long-term outcomes when compared to vegetative states or coma. Abraham 1ġ Department of Neurological Surgery, University of California, San Diego, La Jolla, CA, USA Ģ Department of Neurological Surgery, University of California, Irvine, Orange, CA, USA ģ Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA, USA Ĥ Department of Biomedical Engineering, Johns Hopkins Whiting School of Engineering, Baltimore, MD, USA ĥ Department of Neurological Surgery, Keck School of Medicine of USC, Los Angeles, CA, USA Ħ Department of Biomedical Engineering, California Institute of Technology, Pasadena, CA, USA ħ Department of Anesthesiology PM&R Division, University of California, San Diego, La Jolla, CA, USAĬontributions: (I) Conception and design: ME Abraham (II) Administrative support: None (III) Provision of study materials or patients: None (IV) Collection and assembly of data: AE Choi, LI Ibrahim (V) Data analysis and interpretation: GR Produturi, JS Kurtz, NJ Brown (VI) Manuscript writing: All authors (VII) Final approval of manuscript: All authors.Ībstract: The minimally conscious state (MCS) is a disorder of consciousness described in recent years for patients who have behavioral responses to stimuli that do not meet the classification of chronic vegetative state (CVS) or coma. ![]() Ibrahim 3, Julian Gendreau 4, Shane Shahrestani 5,6, Ronald Sahyouni 1, Joel Castellanos 7, Mickey E. Policy of Dealing with Allegations of Research Misconduct.Policy of Screening for Plagiarism Process.
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